When starting the index tuning advisor, the following error was received:

R6031- Attempt to initialize the CRT more than once.  This indicates a bug in your application.  

Well no sh** sherlock !  Whoever rights these error messages needs their heads examined.

Found a Microsoft KB Article that seems to apply, but we found the key to delete at another location; we have not deleted the key, as we did not want to have the system become unstable, and deleting keys, that were not specified is not advisable.

We found the key at:
HKEY_LOCAL_MACHINE\Software\Microsoft\Windows NT\CurrentVersion\AppCompatFlags\Layers

KB Article says to find key at:
HKEY_CURRENT_USER\Software\Microsoft\Windows NT\CurrentVersion\AppCompatFlags\Layers

KB Article: http://support.microsoft.com/kb/913395 

Picture of Error: